Why do antidepressants have withdrawal symptoms

Antidepressants: be careful when stopping

Tricyclic Antidepressants (NSMRI)Amitriptyline, Clomipramine, Dibenzepine, Desipramine, Doxepin, Imipramine, Nortriptyline, Opipramol, TrimipramineInhibit the re-uptake of messenger substances for signal transmission in the synapses between the nerve cells and block some receptors so that they no longer absorb messenger substances. This increases the concentration of messenger substances in the brain.Weight gain, constipation, tiredness, tremors, dry mouthSelective Serotonin Reuptake Inhibitors (SSRI)Citalopram, fluvoxamine, fluoxetine, paroxetine, sertralineBlock the resumption of the messenger substance serotonin and thus increase the serotonin level. Due to the targeted effect, there are fewer side effects with SSRIs than with the more broadly acting tricyclic antidepressants.Sexual dysfunction, weight gain, fatigue, insomnia, headache, dry mouth, restlessness, nauseaSelective serotonin / norepinephrine reuptake inhibitors (SNRI)Venlafaxine, duloxetineSNRIs work like SSRIs, but they also inhibit the resumption of the "happiness hormone" dopamine and thus also raise the dopamine level.Insomnia, fatigue, dizziness, dry mouth, sexual dysfunctionSelective norepinephrine reuptake inhibitors (NARI)ReboxetineNorepinephrine controls stress resistance, increases motivation, increases alertness and mental performance. NARIs are mainly used in inhibited-depressed patients to relieve depression and listlessness.Insomnia, dry mouth, racing heart, high blood pressure, dizziness, difficulty urinating, erectile dysfunctionMonoamine Oxidase Inhibitors (MAOH)Moclobemide, rasagiline, safinamide, tranylcypromineHave a drive-increasing, mood-enhancing and also somewhat fear-relieving effect. If other antidepressants have failed, MAOH can still have an effect, which is why they are also used in therapy resistance.Interactions with certain types of cheese, blood pressure crises, sleep disorders, headaches, nausea